Journal: BMC Infectious Diseases
Article Title: Evaluating the antibacterial effect of meropenem-loaded chitosan/sodium tripolyphosphate (TPP) nanoparticles on Acinetobacter baumannii isolated from hospitalized patients
doi: 10.1186/s12879-024-09522-7
Figure Lengend Snippet: Assessment of the antibacterial effects of the MP-CS nanoparticles. The antibacterial effects of meropenem, the CS nanoparticles, and the MP-CS nanoparticles on A. baumannii (ATCC19606) strain ( a ), A. baumannii strain #1 ( b ), and A. baumannii strain #2 ( c ) assessed via the well diffusion method. The minimum inhibitory concentrations of the CS nanoparticles and MP-CS nanoparticles on A. baumannii (ATCC19606) strain ( d ), A. baumannii strain #1 ( e ), and A. baumannii strain #2 ( f ). The minimum inhibitory concentrations of meropenem and meropenem encapsulated in the MP-CS nanoparticles (at their corresponding minimum inhibitory concentrations) on A. baumannii (ATCC19606) strain ( g ), A. baumannii strain #1 ( h ), and A. baumannii strain #2 ( i ). NPs, nanoparticles. Data are expressed as mean ± standard deviation. All experiments were performed in triplicate ( n = 3). *, **, ***, ****, and ns represent p < 0.05, p < 0.01, p < 0.001, p < 0.0001, and p > 0.05, respectively
Article Snippet: NCI-H292 + A. baumannii ATCC + MP-CS nanoparticles , 12 × 10 6 (100%) , 11.36 × 10 6 (94.67%) , 3.49 × 10 5 (2.91%) , 2.90 × 10 5 (2.42%).
Techniques: Diffusion-based Assay, Standard Deviation